The Potential of Fasting-Mimicking Diet as a Preventive and Curative Strategy for Alzheimer’s Disease

This review examines the potential of fasting-mimicking diets (FMDs) in preventing and treating Alzheimer’s disease (AD). FMDs are low-calorie that mimic physiological metabolic effects fasting, including activation cellular stress response pathways autophagy. Recent studies have shown can reduce amyloid-beta accumulation, tau phosphorylation, inflammation, as well improve cognitive function animal models AD. Human also reported improvements AD biomarkers, functions, subjective well-being measures following FMDs. However, optimal duration frequency their long-term safety efficacy remain to be determined. Despite these uncertainties, hold promise a non-pharmacological approach prevention treatment, further research this area is warranted.